However, reducing Wg in Ras/Src-activated cells (ras1G12V;csk−/−,wgRNAi) fed HDS or in InR/Ras/Src-activated cells (inrCA,ras1G12V;csk−/−,wgRNAi) fed a control diet significantly suppressed tumor growth (Figure 1C,F). Here, CSK is linked to neoplasm.