KRAS and neoplasm: Full tumor RAS testing—rather than solely KRAS exon 2 testing—is included in treatment guidelines for mCRC such as those from the European Society for Medical Oncology (ESMO), the National Comprehensive Cancer Network (NCCN), the German Cancer Society Association of Medical Oncology (AIO), and the Dutch Landelijke Werkgroep Gastro Intestinale Tumoren [38–41].