The notion that concurrent MYC/BCL6 rearrangements in DLBCL is not an indication of aggressive lymphoma was further substantiated by the lack of a distinctive GEP signature for MYC/BCL6 rearranged DLBCL although BCL6 was overexpressed in almost all MYC/BCL6 rearranged patients except one case with an IHC of 30%. The gene discussed is MYC; the disease is lymphoma.