Introduction of miR-494 or miR-599 mimics, and to a greater extent, co-introduction of both, caused inhibition of proliferation in Mel-RM cells, which was abolished by co-introduction of exogenous INPP4B or myr-SGK3 (Figures 6F and 6G), consolidating the functional significance of downregulation of these miRNAs in melanoma cells. Here, SGK3 is linked to melanoma.