LITAF and malignant colon neoplasm: The LPS-induced tumour necrosis factor (TNF)-α factor (LITAF), alternatively known as small integral membrane protein of the lysosome/late endosome (SIMPLE) and as p53 inducible gene-7 (PIG-7) protein, has been initially identified as a p53-inducible target in DLD-1 colon cancer cell lines [13].