TARDBP and Alzheimer disease: Autoradiographic studies on brain specimens of patients with a range of disorders [AD, FTD-tau and PSP, CBD, Parkinsons disease (PD), dementia with Lewy bodies (DLB), and cerebral amyloid angiopathy (CAA)] have shown that while AD brains containing NFTs show high tracer binding, this is not evident in DLB, CAA, and FTD-TDP43.