Based on of an assessment of a continuing lack of evidence for an increased risk of malignancy in donors receiving G-CSF, the WMDA issued a statement in 2012, which endorses that, ‘Studies following large numbers of unrelated donors have shown that the risk of developing cancer within several years after the use of G-CSF is not increased compared with donors not receiving G-CSF’ [73]. This evidence concerns the gene CSF3 and cancer.