All covariates known to affect prognosis after MI including age, gender, smoking status, hypercholesterolaemia, hypertension, history of previous acute myocardial infarction, diagnosis at discharge, discharge prescription of aspirin, clopidogrel, beta-blockers, angiotensin-converting enzyme inhibitors and statins, revascularisation status and glucometabolic status were “entered” into the model. The gene discussed is ACE; the disease is myocardial infarction.