The expression of enzymes involved in GSH metabolism, including glutathione reductase (GSR), GCLC, GSS, glutaredoxin (GLRX), γ-glutamyltransferase 1 (GGT1), glutathione S-transferase alpha 1 (GSTA1), and glutathione S-transferase pi 1 (GSTP1), as well as three selenoproteins, glutathione peroxidase 1 (GPX1), GPX2, and glutathione peroxidase 4 (GPX4), in tumor and surrounding normal tissue samples from the three lung and three liver cancer patients were examined in duplicate by western blotting (Figure 2A–C). This evidence concerns the gene GCLC and liver cancer.