ACHE and status epilepticus: The underlying mechanism of OP-induced toxicity is the inhibition of AChE which in turn leads to the excessive accumulation of the excitatory neurotransmitter acetylcholine (ACH) within synapses (the cholinergic phase) resulting in a plethora of signs and symptoms including Status epilepticus; overactivation of muscarinic receptors results in the generation of seizures and Status epilepticus [38,39,40,41,42,43].