That various potential genes identified by the genome-wide association study (e. g., ALDH18A1, EPB41L4B, FGF3, and FGF4) and all but 1 gene identified in the rare variant analysis have been shown to possess tumorogenic potential should not be surprising since various genes shown to play roles in the progression of various cancers also play critical roles in wound healing, cellular migration, cellular integrity, and angiogenesis [60, 122, 123]. The gene discussed is EPB41L4B; the disease is cancer.