These components include fibrinogen, fibronectin, collagen, cytokeratin 10, elastin, heparan sulfate proteoglycans, von Willebrand factor, bone sialoprotein, vitronectin, and prothrombin that all facilitate the colonization of diverse tissues and accounts in part for the myriad of diseases than can result following infection with this pathogen [119–121]. Here, VWF is linked to infection.