As shown in the IMGT/HLA database (http://www.ebi.ac.uk/imgt/hla), over 40 polymorphic alleles have been found in exon 2 to 6 of MICB. Specific polymorphisms are associated with autoimmune diseases, cancer, and infectious diseases, as well as with the success of hematopoietic stem cell transplantation. Here, MICB is linked to infectious disease.