PARK7 and non-small cell lung carcinoma: Another proteomic study found that the treatment of paclitaxel combined with MEK inhibitor significantly alters the level of RS/DJ-1 (RNA-binding regulatory subunit/DJ-1 PARK7) and RhoGDIα (Rho GDP-dissociation inhibitor α) in NSCLC H157 cell line, suggesting an important role that RS/DJ-1 and RhoGDIα are involved in drug resistance [30].