With regard to the monogenic model of obesity, the ob/ob mice exhibit a high body weight (Figure 1(b)) and food intake (Figure 1(f)), and similar to the DIO rats, the ob/ob mice display a significant increase in insulin, glucose, and cholesterol levels with respect to WT controls (Table 1) and high levels of inflammatory markers in WAT (Figure 2(b)). This evidence concerns the gene INS and Obesity.