CD8A and neoplasm: We next extended our observations to other antigen specificities by using four additional multimers (hTERT1572-580, human CMV pp65495-503, Ebola NP202-210 (Sundar et al., 2007), HIV-1 Gag p1777-85) that are expected to detect inexperienced self- and virus-specific CD8+ T cell populations in tumor-free, CMV-, Ebola- and HIV- seronegative individuals.