FATE1 and neoplasm: In the cleavedcaspase-3/7 survival screen, depletion of FATE1 elevated the activity of theseexecutioner caspases greater than twofold, a phenotype that was also detectableby immunoblot in a range of tumorigenic settings and suggests that FATE1 isessential for tumour cell survival (Fig. 2c and Supplementary Fig. 2b).