While displaying gene expression in accordance with an activated phenotype, all mature T-cell lymphoma samples additionally differentially regulated genes involved in effector T-cell differentiation (GILZ, TNFRSF21, STAT5A, RICTOR), T-cell homeostasis (FOXP1 and HVEM), and upregulating an immature thymocyte marker (Thy-1/CD90) [41]. The gene discussed is TNFRSF14; the disease is T-cell non-Hodgkin lymphoma.