A multivariate analysis showed that HOXB1 expression (HR 0.030, P = 0.001, 95% CI 0.004–0.261) and glioma grade (HR 4.682, P = 0.021, 95% CI 1.257–17.439) were associated with shorter survival (Table 2). The gene discussed is HOXB1; the disease is central nervous system cancer.