The expression of three cytokines (IL-1α, IL-5, and TNF-α) and nine chemokines (CCL4, CCL17, CCL18, CCL21, CCL23, CXCL1, CXCL2, CXCL3, and CXCL5) was lower in the tumor samples than in the normal controls (Figure 1A). This evidence concerns the gene TNF and neoplasm.