We tested the epithelial mesenchymal transition (EMT) phenotypes that are associated with cancer progression and metastasis (Kalluri and Weinberg, 2009) in tumor samples from the BaP-treated A/J mice, and found that the expression of E-Cadherin was down-regulated, while N-Cadherin, Vimentin, Slug and Snail were up-regulated (Figure 6—figure supplement 1A). This evidence concerns the gene CDH1 and cancer.