CXCL12 and CCR7 regulate the metastasis of breast cancers and NSCLCs (Phillips et al., 2003; Müller et al., 2001; Takanami, 2003), while CXCL1/2 enhance cell survival and promote chemoresistance (Acharyya et al., 2012). Here, CXCL12 is linked to breast carcinoma.