HLA-DRB1 and type 1 diabetes mellitus: This observation is consistent with the findings of Bearzatto et al [8], who found that antibodies to the JM2 epitope in the absence of those to JM1 (cluster 3 in our study) were found in relatives of individuals with type 1 diabetes with HLA-DRB1*03/DRB1*04, DRB1*01/DRB1*04 or DRB1*04/DRB1*13 genotypes.