ROCK1 and hereditary clear cell renal cell carcinoma: miR-584 was shown to decrease cell motility through the inhibition of Rho-associated coiled-coil-containing protein kinase 1 (ROCK-1) in renal cell carcinoma (RCC) cell lines, and the expression of miR-584 was inversely correlated with that of ROCK-1 in RCC tissues [98].