ANO1 and hypertensive disorder: For example, TMEM16A is abundantly expressed in vascular smooth muscle (Davis et al., 2010; Manoury et al., 2010; Thomas‐Gatewood et al., 2011; Heinze et al., 2014; Wang et al., 2015) where TMEM16A channel openers and blockers could be employed to treat hypotension and hypertension respectively.