As IRF1 is a transcription factor critical for IFNγ signaling by driving downstream expression of many IFNγ target genes [19], we also assessed if knock down of IRF1 in M-CSF-treated and M-CSF/IFNγ-treated macrophages altered infection of EBOV GP/rVSV in peritoneal macrophages. The gene discussed is CSF1; the disease is infection.