(Corbin et al., 2011; Li et al., 2012; Petzer et al., 1996; Sloma et al., 2010; Udomsakdi et al., 1992b) Similar to normal HSCs, CML LSCs express typical markers of primitive hematopoietic cells including, CD34 and CD90, and are negative for hematopoietic lineage markers (lin−) and CD45RA (Udomsakdi et al., 1992b). The gene discussed is CD34; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.