SPN and chronic myelogenous leukemia, BCR-ABL1 positive: In OP9 coculture, CML iPSCs and control bone marrow-derived iPSCs (BM1K and BM9) formed CD34+CD43+ hematopoietic progenitors, including CD235a−CD41a−CD45+ cells that are highly enriched in myeloid progenitors (Hu et al., 2011; Vodyanik et al., 2006) (Fig. 1a and b).