CML iPSC-derived lin−CD34+CD90+CD117+CD45+38+/− (hereafter referred to as induced CD34+; iCD34+) cells acquired expression of myeloid lineage-specific markers and lost CD34 expression (Fig. 1b, day 15), i.e. became lin+CD34− (hereafter referred to as induced CD34− cells; iCD34−) following further culture with hematopoietic cytokines. This evidence concerns the gene THY1 and chronic myelogenous leukemia, BCR-ABL1 positive.