Therefore, to assess the role of OLFM4 in vivo, we performed transplantation of somatic lin−CD34+ cells from CML patients in chronic phase using NOD,B6.SCID IL2Rγ−/− KitW41/W41 (NBSGW mice possessing a defective Kit allele; c-kit, W41) (McIntosh et al., 2014). The gene discussed is IL2RG; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.