Along the increasing insulin resistance tertiles, the variables AEA (Fig 2A), 2- AG (Fig 2B), BMI, WC, WHR, SBP, DBP, MBP, glucose, triglycerides, insulin, leptin, hsCRP (all P<0.001) and OEA (P = 0.03), exhibited a significant increasing trend, whereas HDL-cholesterol (P<0.001), HMW adiponectin (P<0.001) and PEA (Fig 2C) decreased. The gene discussed is INS; the disease is Insulin resistance.