ADIPOQ and Insulin resistance: The present study investigates subjects with a wide BMI range via quantitative measurement of circulating eCBs and their related compounds as well as genotyping for the 385C>A polymorphism in FAAH. These variables are used to identify the obese phenotype associated with insulin resistance, dysregulation of adipocytokines (leptin and high molecular weight adiponectin) and cardiometabolic biomarkers.