We observed significant association of TNF-α -238 (AA), IL-1α-889 (CC) and IL-10-1082(GG) genotype in sepsis and IL-1β -511 (CT), IL-1RpstI1970 (TT) and TGFβ codon25 (GG) genotype in non-survivors. This evidence concerns the gene IL10 and Sepsis.