HDAC2 and ovarian carcinoma: Analysis of the effect of specific isoforms of HDACs using siRNA against HDAC1, HDAC2 and HDAC3 on the ovarian carcinoma cell lines, SKOV3, OVCAR3, IGROV-1, ES-2, TOV112D, A2780 and A2780/CDDP showed that knockdown of HDAC1 considerably reduced the proliferation of ovarian carcinoma cells, while knockdown of HDAC3 reduced cell migration (Hayashi et al. 2010).