CRP and chronic kidney disease: However, it is remarkable that regarding the effect sizes in the CKD/pre-KT subgroup, there are a number of medium (r = 0.3–0.49) to large (r ≥ 0.5) effects, which indicates relations among depressive coping, active coping and trivializing/wishful thinking and S-creatinine, as well as partly CRP (Table 3).