CEACAM5 and colorectal carcinoma: The availability in clinicopathologic investigation on colorectal carcinoma of carbohydrate antigen 19-9 (CA19-9) has been demonstrated in many reports,10–16 although its sensitive to detect colorectal carcinoma has been reported to be less than does CEA, and to this date its role for screening, staging, and treatment monitoring for CRC cannot be recommended due to insufficient data.9 However, the possible application of CA19-9 values in prognosis is still controversial.