AMD1 and obesity due to melanocortin 4 receptor deficiency: Albeit we found no association between AMD1 rs2796749 and risk of obesity, the AMD1 (rs2796749) G-allele strongly correlated with a lower zBMI among the TDCOB non-obese children and borderline with the TDCOB obese children but not among the GOYA men, suggesting some protective effect of AMD1 SNP on BMI among children but not young men.