Albeit we found no association between AMD1 rs2796749 and risk of obesity, the AMD1 (rs2796749) G-allele strongly correlated with a lower zBMI among the TDCOB non-obese children and borderline with the TDCOB obese children but not among the GOYA men, suggesting some protective effect of AMD1 SNP on BMI among children but not young men. The gene discussed is AMD1; the disease is obesity disorder.