TP53 and central nervous system cancer: The chromosomal regions 7q, 8q, 9p, 11p, and 12p contain various oncogenes or tumor suppressor genes, including MET (7q31), MYC (8q24.21), CDKN2A (9p21), CDKN1C (11p15.5), and KRAS (12p12.1), and these genes might be associated with tumor progression in IDH mutant gliomas with TP53 mutations.