KLK3 and posterior cortical atrophy: Early phase-I and phase-II clinical trial results of dietary-derived agents, such as lycopene, curcumin, and isoflavone, show that they are well tolerated and have favourable effects on PCa activity markers, such as prostate-specific antigen (PSA) and serum testosterone levels [10, 11]; however, further evidence is needed to determine their value for the prevention or treatment of PCa.