PGF and chronic kidney disease: Regardless of the clinical diagnosis (PE, CKD, or others), a higher ratio and the presence of impaired uteroplacental flow were significantly associated with preterm delivery and SGA babies: the median sFlt-1/PlGF ratio was 9.07 (min 1.04; max 137.40) in the 31 patients who delivered at or after 37 weeks; it was 28.59 (1.86–356.58) in the cases who delivered at 34–37 weeks and 376.21 for patients who delivered before 34 weeks, once more with a very wide dispersion (min–max: 3.09–2619.11) (P < 0.001).