It has been reported that stimulation of A549 cells with LPS, PGN or Klebsiella pneumonia together with recombinant sCD14 increases the release of chemokines, such as CXCL8 compared with stimulation with LPS, PGN, and Klebsiella pneumonia alone (15–17). The gene discussed is CXCL8; the disease is Klebsiella pneumonia.