When lung adenocarcinoma patients from another independent cohort (n = 332; MGH + ACC + Nagoya, GSE13213 and GSE11969) were divided into two groups according to TIMP-2 expression, Kaplan-Meier plots showed significant differences in OS for only pstage I (p < 0.001; Figure 7E). Here, TIMP2 is linked to lung adenocarcinoma.