SFN and colonic neoplasm: Thymosin β-4 (Tβ-4) and 14-3-3 protein sigma (14-3-3-σ) were the only proteins showing a single identification hit of which Tβ-4 was detected to be differently regulated between diploid and aneuploid colon cancers (Tables 2 & 3; Supplemental data 4 & 5).