Repeating the Textrous! NLP analysis for the FLNC p.V831I variant (Fig. 6a), as with the FTD-common dataset, we found strong correlations between the words ‘neuronal-Wiskott–Aldrich Syndrome protein (N-wasp)’, ‘cytoskeleton’, ‘neurites’, ‘microtubules’ and ‘filopodia’ and following proteins: CAP-GLY domain containing linker protein 1 (CLIP1), Wiskott-Aldrich syndrome protein family member 3 (WASF3), Myc box-dependent-interacting protein 1 (BIN1) and microtubule-associated protein 4 (MAP4). This evidence concerns the gene CLIP1 and frontotemporal dementia.