A number of FLNC variations - p.R81C, p.K524R, p.D710N, p.R1241C, and p.T2025I - were identified in FTD patients who carried a causal mutation in another FTD gene i.e. FLNC p.R1241C in a VCP p.R159H carrier, FLNC p.R81C and p.T2025I in GRN loss-of-function mutation carriers [10], and FLNC p.K524R and p.D710N in C9orf72 repeat expansion carriers [11] (Table 2, Additional file 1: Table S3b). The gene discussed is C9orf72; the disease is frontotemporal dementia.