The median frequencies of CD34+-HSPC and mature CD45-CD34+VEGFR2+-EPC were significantly decreased in malaria patients relative to non-malaria subjects; 0.5 (IQR 0.3–0.9) in non-malaria vs. 0.2 (0.1–0.3) in malaria patients, p = 0.0006 and 0.3 (IQR 0.1–0.7) in non-malaria vs. 0.1 (IQR 0.1–0.2) in malaria patients, p = 0.02 (Fig 2A and 2B. The gene discussed is PTPRC; the disease is malaria.