FOSB and epilepsy: As different factors are able to induce fosB expression [40], the observed changes in FosB/ΔFosB immunoreactivity may not be related to epileptic activation of neuronal networks; however, changes similar to those observed in the 6-Hz corneal stimulation paradigm have been found in several models of epilepsy [10–15] and after exposure to electroconvulsive seizures [41].