SCN1A and epilepsy: Genotyping these two SNPs in epileptic patients and healthy controls revealed that carriers of the SCN1A IVS5-91G>A variant were at increased risk of epilepsy susceptibility (P = 0.033; OR 1.80, 95% CI 1.048, 3.094), while no impact for SCN1A c.3184A>G SNP was observed (Fig 2).