MYCN and small cell lung carcinoma: In SCLC, inactivating MAX mutations were found to be mutually exclusive with amplifications of hetero-dimeric partners MYC, MYCL1, and MYCN, and mutations in BRG1, which encodes an ATPase of the SWI/SNF chromatin -remodeling complex that regulates expression of MYC, MYC target genes, as well as MAX.