Ezrin (EZR, Spot F172), myosin regulatory light chain (MRLC2, Spot F323), myosin regulatory light chain 12B isoform 2 (MLC-2A, Spot F85), beta-actin (ACTB, Spot F195), tublin alpha-3 (TUBA1B, Spot F164) and actin-related protein 3 (ARP3, Spot F19) were significantly up regulated in the IUGR placenta. The gene discussed is ACTR3; the disease is fetal growth restriction.