For example, Hollis-Moffatt et al demonstrated evidence that GLUT9 polymorphisms play a significant role in modifying the risk of gout, including rs16890979, rs11942223, rs11942223, and rs5028843.13 Disappointedly, this finding was not replicated among samples of Chinese ancestry.14 The genetic effects of GLUT9 polymorphisms may be underestimated due to the limited sample size of published studies. The gene discussed is SLC2A9; the disease is gout.