MiR-205 inhibits VEGF-A and further suppresses human glioblastoma cell growth.34 As for colorectal cancer, miR-205 can be used as biomarker to differentiate lymph node metastatic colorectal cancers from nonmetastatic colorectal cancers.35 MiR-205 is significantly decreased in gastric cancer patients compared with healthy controls.36 Our study revealed a low level of miR-205 in ESCC patients as well. This evidence concerns the gene VEGFA and colorectal cancer.