VIM and breast cancer: However, by comparing the expression of epithelial (E-cadherin or Ecad) and mesenchymal (vimentin or Vim) markers between MCF10A and two breast cancer cell lines well-characterized for their cellular states (MCF7 = E state, MDA-MB231 = metastatic human breast cancer cells corresponding to an M state), we found MCF10A cells to be likely in a state that is intermediate between typical terminal E and M cells (Fig 3A, compare green population to others; S1 Fig).