Detailed analysis of the 12q13 locus encompassing coding variants in ATF1 and FAM186A showed that three new variants are within a region of fairly extensive linkage disequilibrium (LD) (r2 = 0.31–0.68, D’ = 0.92–1) and in moderate LD with rs11169552, a previously identified through GWAS10 CRC risk locus (r2 = 0.08 − 0.24, D’ = 0.95–0.99). Here, ATF1 is linked to colorectal carcinoma.