IL6 and endothelial dysfunction: The Multiethnic Study of Atherosclerosis (MESA) reported that both FEV1 and FVC are positively associated with small artery elasticity, and inversely associated with serum markers of endothelial dysfunction and inflammation such as intercellular adhesion molecule 1 (ICAM-1), fibrinogen, C-reactive protein (CRP), and interleukin 6 (IL-6) [11].