The Multiethnic Study of Atherosclerosis (MESA) reported that both FEV1 and FVC are positively associated with small artery elasticity, and inversely associated with serum markers of endothelial dysfunction and inflammation such as intercellular adhesion molecule 1 (ICAM-1), fibrinogen, C-reactive protein (CRP), and interleukin 6 (IL-6) [11]. The gene discussed is ICAM1; the disease is endothelial dysfunction.