BRCA1 and breast carcinoma: To ascertain whether CHEK2*1100delC breast cancers harbor characteristic genomic aberrations, as seen in BRCA1 mutated breast cancers, we specifically compared the genomic profiles of 14 CHEK2*1100delC breast cancers and 34 BRCAX breast cancers of the luminal intrinsic subtypes for which both SNP-array and gene expression data is available.