TGFB1 and infection: As shown in Fig. 8b, shMLL1 and shSET7/9 co-infection completely inhibited TGFβ1-induced TGFBIp mRNA levels compared with shMLL1 or shSET7/9 single infection, providing evidence that both MLL1 and SET7/9 mediate TGFβ1-induced TGFBIp expression by regulating H3K4me1/3.