In the IR/HR group for localized ccRCC, significant difference was found in OS (p = 0.015) and DFS (p = 0.002) according to the ST3GAL-1 expression (Fig. 3b, d), however ST3GAL-1 failed to further stratify patients with different prognosis in UISS LR patients (Fig. 3a, c). This evidence concerns the gene ST3GAL1 and nonpapillary renal cell carcinoma.